GET ContentService/data/orthology/{id}/species/{speciesId}

reactome.org:reactome-api

Summary: The orthology for a given event or entity
Operation ID: getOrthology
Auth: unknown
Description

Reactome uses the set of manually curated human reactions to computationally infer reactions in twenty evolutionarily divergent eukaryotic species for which high-quality whole-genome sequence data are available, and hence a comprehensive and high-quality set of protein predictions exists. Thus, this method retrieves the orthology for any given event or entity in the specified species. <a href="//www.reactome.org/pages/documentation/electronically-inferred-events/" target="_blank">Here</a> you can find more information about the computationally inferred events.

Parameters (4)

id (string, path, required)

The event for which the orthology is requested

includeRef (boolean, query, optional, default: False)

Global parameter - If true, replace element ref to dbId by standard JSOG object {@ref}

speciesId (integer, path, required)

The species for which the orthology is requested

view (string, query, optional, default: flatten)

Global parameter - Customise the view to be more concise and/or aggregate relationships

Constraints: {'enum': ['flatten', 'nested', 'nested-aggregated']}

Examples (1)

TitleTypeURLAction
The orthology for a given event or entity openapi-spec https://reactome.org/ContentService/data/orthology/R-HSA-6799198/species/49633

Probe History

Latency

Status Codes

TimeStatusLatencySize
2026-03-23 10:55:12.683070 200 333ms