GET /proteomes/search

uniprot.org:uniprot-api

Summary: Search proteomes
Operation ID: searchProteomes
Auth: none

Search UniProt Proteomes for complete sets of proteins from fully sequenced organisms. A proteome represents all the proteins encoded by the genome of a specific organism, including chromosomal proteins, plasmid proteins, and organelle-encoded proteins. Use this endpoint when you need information about complete proteome sets rather than individual proteins. Results include proteome statistics, genome assembly information, and component breakdowns (e.g., which chromosomes/proteins are included). This is useful for comparative genomics, proteome-wide analyses, and understanding the complete protein complement of an organism.

Original spec description

Search proteomes (complete sets of proteins expressed by an organism).

Usage Tips

- Proteome IDs follow the pattern UP000005640 (human reference proteome) - Results include `proteomeType` indicating if it's a reference proteome - `components` lists genome components (chromosomes, organelles) with protein counts - Each component shows annotation source (e.g., Ensembl) and genome accession - Use `organism:` query syntax to search by organism name - The `taxonomy` field shows the organism's scientific name, common name, and NCBI taxon ID - Reference proteomes are manually selected high-quality representative sets

Parameters (3)

format (string, query, optional, default: json)

Constraints: {'enum': ['json', 'xml']}

query (string, query, required)

Search query string

size (integer, query, optional, default: 25)

Examples (3)

TitleTypeURLAction
Search for human proteome curl https://rest.uniprot.org/proteomes/search?query=human
Search with size limit curl https://rest.uniprot.org/proteomes/search?query=Arabidopsis&size=5
Search by taxonomy ID curl https://rest.uniprot.org/proteomes/search?query=organism:9606

Probe History

Latency

Status Codes

TimeStatusLatencySize
2026-03-23 09:18:33.437503 200 147ms
2026-03-23 09:08:29.999239 200 136ms
2026-03-23 09:00:22.836223 400 171ms

Response Changes

WhenOldNew
2026-03-23 09:08:29.999239 d0dad97cc5b0 f4dfb867bc1b
2026-03-23 09:18:33.437503 f4dfb867bc1b 64ab6aa01921